An overarching hypothetical model for the regulation of epithelial transcriptome in tumor progression and the co-evolving host immune response. This model emphasizes the inhibition of histone deacetylase 1 as the underlying mechanisms for the biological functions of maspin and suggests the therapeutic potential of novel maspin-based drugs in eliminating invasive and metastatic cancer.
An overarching hypothetical model for the regulation of epithelial transcriptome in tumor progression and the co-evolving host immune response.
An overarching hypothetical model for the regulation of epithelial transcriptome in tumor progression and the co-evolving host immune response. This model emphasizes the inhibition of histone deacetylase 1 as the underlying mechanisms for the biological functions of maspin and suggests the therapeutic potential of novel maspin-based drugs in eliminating invasive and metastatic cancer.
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