Le et al. recently reported (Science 10.1126/science.aan6733 (2017); (ClinicalTrials.gov number, NCT01876511) on the success of immune checkpoint blockade with anti-PD-1 antibodies in the patients whose cancers exhibited microsatellite instability-high (MSI-H) status. The study included 12 […]
We are delighted to announce a great news from the Bosnian Journal of Basic Medical Sciences (BJBMS). The Journal’s 2016 Impact Factor (IF), recently released by Thomson Reuters (Journal Citation Reports) is 0.906! This represents more […]
Targeted therapy based on the immune checkpoint inhibitors (Anti-PD1/PD-L1) has revolutionized cancer treatment and outcome of several solid and hematologic malignancies, including non-small cell lung carcinoma (NSCLC), metastatic renal cell carcinoma, metastatic malignant melanoma, advanced/metastatic […]
May 2017 issue of Bosnian Journal of Basic Medical Sciences (BJBMS) is published. As with the previous issues, we cover many fields of basic medical, as well as translational medical research in this issue. See the […]
Colorectal cancer is one of the most prevalent and lethal disorders worldwide. There is an increseas in its incidence during the last two decades. Besides the environmental contributing factors, genetic variations are also responsible for […]
Perinatal hypoxia-ischemia is an important pathological event in everyday neonatal practice. Numerous studies have found that a newborn reacts on perinatal hypoxic events with its whole body. Short-term hypoxia effects can be acute or chronic, of […]
It is becoming clear that tumor consists of heterogeneous cells. These cells are different one to another in terms of their capacity to proliferate and to survive against cancer therapy, such as chemotherapy, radiotherapy and […]
Type 1 diabetes mellitus (T1DM) results from autoimmune destruction of pancreatic β-cells after an asymptomatic period over years. Insulitis activates antigen presenting cells, which trigger activating CD4+ helper-T cells, releasing chemokines/cytokines. Cytokines activate CD8+ cytotoxic–T […]
More than 70% of women will experience candida infections once or more in their lifetime. About 5% to 10% of patients may experience recurrent vulvovaginal candidiasis (RVVC). Candida albicans is the main pathogen of candidiasis. […]
Thyroid cancer is occurs when abnormal cells begin to grow in a thyroid gland. It is the most frequent cancer among endocrine gland cancers. Most thyroid cancers are curable, because the cancer is usually found […]
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