MRI of three different patiens from one family (mother, son, doughter). a) axial T2-weighted image shows characteristic changes in CADASIL – anterior temporal pole hyperintensities; b,d,g) axial T2-weighted images show periventricular hyperintensities; f) coronal T2-weighted image shows periventricular hyperintensities; c,e,h) axial T2-weighted images show hyperintensities in the deep white matter.