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Home2017

Year: 2017

Tumor suppressor maspin as a modulator of host immune response to cancer
Author Summary

Tumor suppressor maspin as a modulator of host immune response to cancer

January 1, 2017 0

Despite the promising clinical outcome, the primary challenge of the curative cancer immunotherapy is to overcome the dichotomy of the immune response: tumor-evoked immunostimulatory versus tumor-induced immunosuppressive. The goal needs to be two-fold, to re-establish […]

Dystrophin and the two related genetic diseases, Duchenne and Becker muscular dystrophies
Author Summary

Dystrophin and the two related genetic diseases, Duchenne and Becker muscular dystrophies

January 1, 2017 0

Mutations of the dystrophin DMD gene, essentially deletions of one or several exons, are the cause of two devastating and to date incurable diseases, Duchenne (DMD) and Becker (BMD) muscular dystrophies. Depending upon the preservation […]

Lyme Borreliosis: is there a preexisting (natural) variation in antimicrobial susceptibility among Borrelia burgdorferi strains?
Author Summary

Lyme Borreliosis: is there a preexisting (natural) variation in antimicrobial susceptibility among Borrelia burgdorferi strains?

January 1, 2017 0

The development of antibiotics changed the world of medicine and has saved countless human and animal lives. Bacterial resistance/tolerance to antibiotics have spread silently across the world and has emerged as a major public health […]

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