Dr. Tatsuo Tomita, principal investigator and author, is affiliated with Departments of Integrative Bioscience and Pathology, Oregon Health and Science University, Portland, Oregon, USA
Author Summaries

Apoptosis of pancreatic β-cells in Type 1 diabetes

April 17, 2017 0

Type 1 diabetes mellitus (T1DM) results from autoimmune destruction of pancreatic β-cells after an asymptomatic period over years. Insulitis activates antigen presenting cells, which trigger activating CD4+ helper-T cells, releasing chemokines/cytokines. Cytokines activate CD8+ cytotoxic–T […]