![Gross view of mouse male urogenital organs. (A) Anterior and (C) posterior aspects of the urogenital tract dissected from an adult male mouse, as seen under the dissecting microscope. Urethra (U), Seminal vesicles (SV); (B) and (D) show the same images with dashed and dotted lines delineating the ventral (VP), lateral (LP), anterior (AP), and dorsal (DP) prostate lobes; (E) Anterolateral view (left side) of the prostate lobes relative to the bladder, seminal vesicles, and urethra (Modified from: Sugimura, Y., et al. [15]). Scale bar, 1 cm.](https://blog.bjbms.org/wp-content/uploads/2017/01/BJBMS-16-8-g002-326x245.jpg)
Despite substantial similarities in embryological, cellular and molecular biology features, human and mouse prostates differ in organ morphology and tissue architecture. Thus, a clear understanding of the anatomy and histology of the mouse prostate is […]
Pancreatic islet α-cell tumours that overexpress proglucagon are typically associated with the glucagonoma syndrome, a rare disease entity characterised by necrolytic migratory erythema, impaired glucose tolerance, thromboembolic complications and psychiatric disturbances. Paraneoplastic phenomena associated with […]
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is an autosomal dominant vascular disorder. Diagnosis and follow-up in patients with CADASIL are based mainly on magnetic resonance imaging (MRI). MRI shows white matter […]
Reactive stromal changes that occur in different human cancers might play a role in local tumor spreading and progression. Studies done on various human cancers have shown activated stromal cell phenotypes, modified extracellular matrix (ECM) […]
Despite the promising clinical outcome, the primary challenge of the curative cancer immunotherapy is to overcome the dichotomy of the immune response: tumor-evoked immunostimulatory versus tumor-induced immunosuppressive. The goal needs to be two-fold, to re-establish […]
Mutations of the dystrophin DMD gene, essentially deletions of one or several exons, are the cause of two devastating and to date incurable diseases, Duchenne (DMD) and Becker (BMD) muscular dystrophies. Depending upon the preservation […]
The development of antibiotics changed the world of medicine and has saved countless human and animal lives. Bacterial resistance/tolerance to antibiotics have spread silently across the world and has emerged as a major public health […]
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